Metopimazine is primarily used as an antiemetic, effectively preventing and treating nausea and vomiting. It is commonly prescribed for managing symptoms associated with gastrointestinal disorders, migraines, and postoperative recovery. Its application extends to palliative care, where it helps alleviate nausea in patients undergoing chemotherapy or suffering from terminal illnesses. Additionally, it is utilized in pediatric care to address vomiting in children. The drug works by blocking dopamine receptors in the chemoreceptor trigger zone, providing relief without significant sedation. Its efficacy and tolerability make it a preferred choice in various clinical settings for controlling emesis.