Tetramethylammonium acetate is commonly used as a phase-transfer catalyst in organic synthesis, facilitating the transfer of reactants between immiscible phases. It is also employed in the preparation of ionic liquids, which are used in various electrochemical applications. Additionally, it serves as a buffer in biochemical research, helping to maintain stable pH conditions in enzymatic reactions. In the field of materials science, it is utilized in the synthesis of polymers and nanomaterials, where it aids in controlling the morphology and properties of the final product. Its role in analytical chemistry includes acting as a mobile phase additive in chromatography, improving the separation of complex mixtures.