Dimethindene maleate is primarily used as an antihistamine to alleviate symptoms associated with allergic reactions. It effectively reduces itching, sneezing, and runny nose caused by conditions like hay fever, allergic rhinitis, or skin allergies. The compound is often incorporated into topical creams, ointments, or oral formulations to provide relief from allergic skin reactions, insect bites, or hives. Additionally, it is sometimes included in combination products with other active ingredients to address multiple symptoms of colds or allergies. Its ability to block histamine receptors makes it a valuable component in managing mild to moderate allergic conditions.