Pizotifen Malate is primarily used in the prevention of migraine headaches. It works by blocking serotonin receptors and reducing the frequency and severity of migraines. Additionally, it has antihistamine properties, making it effective in managing allergic conditions such as chronic urticaria. It is also sometimes prescribed for its sedative effects to help with sleep disturbances in certain patients. The medication is typically taken orally and requires consistent use for optimal results.