Moxonidine is primarily used in the management of hypertension (high blood pressure). It works by stimulating imidazoline receptors in the brain, which leads to a reduction in sympathetic nervous system activity, thereby lowering blood pressure. This makes it an effective option for patients who require long-term control of hypertension. Additionally, moxonidine has shown potential benefits in improving insulin sensitivity, making it a suitable choice for hypertensive patients with type 2 diabetes or metabolic syndrome. It is often prescribed when other antihypertensive medications are not well-tolerated or when a patient requires a specific mechanism of action to manage their condition. Its ability to reduce blood pressure without significantly affecting heart rate is another advantage in clinical practice.