Fludrocortisone Acetate Solution is primarily used in the treatment of conditions related to adrenal insufficiency, such as Addison's disease. It helps regulate sodium and potassium levels in the body, maintaining fluid balance and blood pressure. The solution is also effective in managing salt-losing forms of congenital adrenal hyperplasia, where the body struggles to produce sufficient hormones. Additionally, it is sometimes prescribed for orthostatic hypotension to improve blood pressure stability upon standing. Its mineralocorticoid activity makes it a critical component in hormone replacement therapy for patients with adrenal gland disorders.