Acamprosate calcium is primarily used in the treatment of alcohol dependence. It helps restore the natural balance of neurotransmitters in the brain, which can be disrupted by long-term alcohol use. By stabilizing brain activity, it reduces cravings and the urge to drink alcohol, supporting individuals in maintaining sobriety. It is often prescribed as part of a comprehensive treatment program that includes counseling and behavioral therapy. The medication is particularly effective for those who have already stopped drinking and are seeking to avoid relapse. It is not intended for use during acute alcohol withdrawal but rather as a long-term aid in recovery.