Nilotinib
98%
Reagent
Code: #51939
Alias
4-methyl-3-((4-(3-pyridyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(tri Fluoromethyl)phenyl)benzamide
CAS Number
641571-10-0
science Other reagents with same CAS 641571-10-0
blur_circular Chemical Specifications
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Molecular Information
Weight
529.52 g/mol
Formula
C₂₈H₂₂F₃N₇O
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Storage & Handling
Density
1.36 g/cm3
Storage
-20°C
description Product Description
Nilotinib is a selective BCR-ABL tyrosine kinase inhibitor, primarily researched for its role in treating chronic myeloid leukemia (CML), a type of blood cancer caused by the BCR-ABL fusion gene. It targets the abnormal BCR-ABL protein that drives excessive leukemia cell proliferation. This compound is used in pharmaceutical research, particularly for patients resistant or intolerant to prior therapies like imatinib. As a reagent, it is supplied as a white to grey powder or solid with 98-100% purity (HPLC). Chemical formula: C28H22F3N7O. Molecular weight: 529.48 g/mol.
format_list_bulleted Product Specification
| Test Parameter | Specification |
|---|---|
| Purity | 98-100% |
| Appearance | White to grey powder or solid |
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