Used in cell culture and biopharmaceutical manufacturing to support the growth and differentiation of cells, particularly in the production of monoclonal antibodies and recombinant proteins. It plays a key role in regulating metabolic activity in cultured mammalian cells, improving productivity and process consistency. Commonly included in media formulations for CHO (Chinese Hamster Ovary) and other industrial cell lines. Also utilized in research settings to study thyroid hormone effects on metabolism, development, and gene expression.