[SP-4-2-(1R-trans)]-(1,2-Cyclohexanediamine-kappaN,kappaN') Diiodoplatinum
98%
Reagent
Code: #238098
CAS Number
66845-32-7
blur_circular Chemical Specifications
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Molecular Information
Weight
561.07 g/mol
Formula
C₆H₁₂I₂N₂Pt
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Storage & Handling
Storage
Room temperature
description Product Description
This platinum complex serves as a key intermediate in the synthesis of platinum-based antitumor agents, such as oxaliplatin, used in chemotherapy for solid tumors including colorectal, ovarian, and lung cancers. The final drugs derived from it bind to DNA, inducing cross-links that disrupt replication and transcription, leading to apoptosis in cancer cells. Its specific (1R-trans) stereochemistry enables the production of agents with improved selectivity and reduced nephrotoxicity compared to cisplatin. Ongoing research explores its role in developing targeted therapies leveraging its controlled reactivity.
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