Used in bioseparation and diagnostic applications due to their uniform size and magnetic responsiveness. The silica shell allows easy surface functionalization with antibodies, proteins, or nucleic acids, enabling targeted capture of biomolecules. Commonly applied in automated immunoassays, DNA/RNA purification, and cell isolation. Their monodispersity ensures consistent performance in magnetic separation systems, while the core-shell structure provides high magnetic loading with good colloidal stability. Also utilized as a solid support in high-throughput screening and drug delivery research.