Widely used in bioseparation and diagnostic applications due to their uniform size and strong magnetic response. Their silica shell provides a stable, biocompatible surface that can be easily modified with functional groups for attaching antibodies, proteins, or nucleic acids. Commonly employed in automated immunoassays, cell isolation, and DNA/RNA extraction, especially in molecular diagnostics and high-throughput screening. The core-shell structure enhances magnetic responsiveness while maintaining colloidal stability, enabling rapid separation under a magnetic field with minimal non-specific binding. Also utilized in targeted drug delivery research and as carriers in microfluidic systems.