Used in bioseparation and diagnostic applications due to their uniform size and magnetic responsiveness. The silica shell allows easy surface modification with functional groups for binding biomolecules such as DNA, RNA, proteins, and antibodies. Commonly applied in automated high-throughput systems for nucleic acid purification, immunoassays, and cell isolation. Their core-shell structure enhances stability and reduces nonspecific binding, improving recovery and purity. Also suitable for use in magnetic bead-based assays and drug delivery research due to tunable surface chemistry and controlled dispersion.