Widely used in bioseparation and diagnostic applications due to their uniform size and strong magnetic response. The silica shell provides a stable, biocompatible surface that can be easily modified with functional groups for covalent coupling of biomolecules such as antibodies, proteins, or nucleic acids. Commonly employed in automated high-throughput systems for DNA/RNA extraction, where the magnetic core allows rapid pull-down using a magnet, minimizing sample handling. Also suitable for targeted drug delivery research and cell isolation, where precise particle size ensures consistent binding and separation efficiency. Their monodispersity enhances reproducibility in assays and improves performance in microfluidic and lab-on-a-chip devices.