Used in bioseparation and diagnostic applications due to their uniform size and magnetic responsiveness. The silica shell allows easy surface modification with functional groups for binding biomolecules such as DNA, RNA, proteins, and antibodies. Commonly applied in automated nucleic acid purification, immunoassays, and cell isolation. Their monodispersity ensures consistent performance in high-throughput systems, while the core-shell structure provides strong magnetic sensitivity with low non-specific binding. Also utilized in drug delivery research and as carriers in microfluidic devices.