Used in bioseparation and diagnostic applications due to their uniform size and magnetic responsiveness. The silica shell allows easy surface functionalization with antibodies, proteins, or DNA for targeted binding. Commonly applied in immunoassays, cell isolation, and nucleic acid purification. Their core-shell structure enhances stability and reduces nonspecific binding, making them ideal for automated high-throughput systems. Also used in drug delivery research and magnetic resonance imaging (MRI) contrast enhancement.