Widely used in bioseparation and diagnostic applications due to their uniform size and strong magnetic response. The silica shell provides a stable, biocompatible surface that can be easily modified with functional groups for coupling antibodies, DNA, or enzymes. These microspheres are ideal for automated high-throughput systems such as magnetic bead-based immunoassays and nucleic acid purification. Their core-shell structure enhances magnetic responsiveness while maintaining colloidal stability, allowing rapid separation under a magnetic field with minimal non-specific binding. Commonly employed in molecular diagnostics, cell isolation, and targeted drug delivery research.