Used in bioseparation and diagnostic applications due to their uniform size and magnetic responsiveness. The silica shell allows easy surface modification with functional groups for binding antibodies, DNA, or enzymes. Commonly applied in immunoassays, nucleic acid purification, and cell isolation. Their monodispersity ensures consistent performance in automated high-throughput systems. Core-shell structure enhances magnetic sensitivity while maintaining colloidal stability in aqueous buffers. Ideal for point-of-care testing and magnetic bead-based assays.