Widely used in biomedical applications due to their uniform size and magnetic responsiveness. Ideal for targeted drug delivery, where the silica shell allows surface functionalization with therapeutic agents while the magnetic core enables guidance and localization under external magnetic fields. Commonly employed in diagnostic assays and bioseparation processes, such as isolation of DNA, RNA, and proteins, thanks to high surface area and easy magnetic separation. Also utilized in imaging techniques like MRI as contrast enhancer carriers. Their core-shell structure protects the magnetic component from oxidation and improves biocompatibility, making them suitable for in vivo applications. Increasingly adopted in lab-on-a-chip devices and automated high-throughput screening systems.