Used in biomedical applications such as targeted drug delivery, where the silica coating allows for easy functionalization with drugs or targeting ligands while preventing aggregation and enhancing biocompatibility. Employed in magnetic separation techniques to isolate DNA, RNA, or specific proteins from complex mixtures due to the high surface area and reversible binding capabilities. Applied in diagnostic assays and biosensors, where the magnetic core enables rapid separation under a magnetic field and the SiO2 shell provides a stable platform for immobilizing biomolecules. Also utilized in catalysis as recoverable catalyst supports, allowing easy separation from reaction mixtures using a magnet and enabling reuse. Common in environmental remediation for removing pollutants from water, where functionalized particles bind contaminants and are then magnetically collected.