Used in biomedical applications such as targeted drug delivery, where the silica coating allows for easy functionalization with drugs or biomolecules while preventing aggregation and enhancing biocompatibility. Employed in magnetic separation techniques to isolate DNA, RNA, or specific proteins from complex mixtures due to the high surface area and ease of recovery using an external magnetic field. Applied in diagnostic imaging as contrast agents in MRI, where the SiO2 layer improves dispersion and reduces toxicity. Also utilized in catalysis, where the magnetic core enables easy catalyst recovery and reuse, and the silica shell can be modified to anchor catalytic species. Common in environmental remediation for removing pollutants from water, followed by magnetic separation.