Used primarily in ophthalmic preparations to treat bacterial infections of the eye, such as conjunctivitis and blepharitis. It is effective against a range of Gram-positive and Gram-negative bacteria by inhibiting bacterial synthesis of folic acid, which is essential for growth. Commonly found in eye drops and ointments, it is well-tolerated and often prescribed for mild to moderate eye infections. Also used in topical formulations for skin conditions like acne vulgaris and seborrheic dermatitis due to its antibacterial and anti-inflammatory properties. Its solubility and stability in aqueous solutions make it suitable for use in sterile eye preparations.