(S)-4-(ethylamino)-2-(3-methoxypropyl)-3,4-dihydro-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide
95%
Reagent
Code: #232800
CAS Number
154127-19-2
blur_circular Chemical Specifications
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Molecular Information
Weight
383.51 g/mol
Formula
C₁₂H₂₁N₃O₅S₃
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Storage & Handling
Storage
2-8°C
description Product Description
This compound, the (S)-enantiomer of a thieno[3,2-e][1,2]thiazine-6-sulfonamide 1,1-dioxide derivative, is a potent carbonic anhydrase inhibitor. It is primarily used in the management of glaucoma by reducing intraocular pressure. By inhibiting carbonic anhydrase II in the ciliary epithelium of the eye, it decreases the production of aqueous humor through reduced bicarbonate formation and subsequent water secretion. This topical agent is effective in lowering elevated intraocular pressure in patients with open-angle glaucoma or ocular hypertension. The (S)-enantiomer demonstrates enhanced potency and metabolic stability relative to the racemic mixture or (R)-enantiomer, allowing for improved therapeutic efficacy at lower concentrations with potentially fewer side effects.
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