Polyethylene-polypropylene glycol is a non-ionic surfactant used in industrial and household cleaning products to reduce surface tension and stabilize emulsions. It is commonly found in detergents, degreasers, and emulsion polymerization processes. It also serves as a defoaming agent and dispersant in water treatment systems.

In personal care products, it functions as an emollient and solubilizer in creams, lotions, and emulsions, enhancing ingredient compatibility and skin softness.

Its low toxicity and good solubility make it suitable for agrochemical formulations to improve the dispersion of active ingredients. It is also used as a solvent or dispersant in pharmaceuticals and medical products, such as suppositories, topical applications, and tablet coatings.

In the paints and printing inks industry, it controls viscosity and prevents foaming. Additionally, it acts as a coupling agent and foam stabilizer in polyurethane foam production, enhancing flexibility, resilience, and uniform structure in applications like mattresses and seat cushions.