Used primarily as an intestinal antibacterial agent, especially in the treatment of bacterial infections of the gastrointestinal tract. It is effective against organisms like Salmonella and Shigella. Due to its limited absorption from the gastrointestinal tract, it acts locally in the intestines, minimizing systemic side effects. Often used in preparation for gastrointestinal surgery to reduce gut flora. Also used in the management of chronic dysentery and other enteric infections. Its action is enhanced when combined with other sulfonamides or antibacterial agents.