Procarbazine Hydrochloride
10mM in Water
Reagent
Code: #224053
CAS Number
366-70-1
blur_circular Chemical Specifications
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Molecular Information
Weight
257.76 g/mol
Formula
C₁₂H₂₀ClN₃O
thermostat
Physical Properties
Melting Point
223 °C
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in the treatment of Hodgkin's lymphoma, often as part of the MOPP regimen (mechlorethamine, vincristine, procarbazine, prednisone). It functions as an alkylating agent and monoamine oxidase inhibitor, interfering with DNA replication and cell division in cancer cells. Also investigated for use in brain tumors due to its ability to cross the blood-brain barrier. Requires careful monitoring due to potential for severe side effects, including myelosuppression and increased risk of secondary malignancies.
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