Used as a broad-spectrum antibiotic, particularly effective against gram-negative bacteria including Pseudomonas aeruginosa, Escherichia coli, and Klebsiella species. Commonly prescribed in hospital settings for treating severe bacterial infections such as urinary tract infections, respiratory tract infections, septicemia, and intra-abdominal infections. Preferred in cases where other aminoglycosides may be less effective or when resistance to gentamicin is present. Due to its mechanism of action, it is often used in combination with beta-lactam antibiotics for synergistic effect. Mainly administered via intravenous or intramuscular routes, and its use is monitored carefully to minimize potential nephrotoxicity and ototoxicity.