Used primarily in the treatment of angina pectoris, it works by dilating blood vessels and reducing the heart's workload. It combines vasodilatory effects through both nitrate-like action and potassium channel activation, improving blood flow to the heart muscle. It is effective in chronic stable angina, helping to increase exercise tolerance and reduce the frequency of angina attacks. Some studies suggest benefits in patients with ischemic heart disease due to its dual mechanism. It may also exhibit cardioprotective properties during ischemia-reperfusion injury, making it useful in specific perioperative cardiac settings.