Used as an isotopically labeled internal standard in analytical chemistry for the accurate quantification of N-nitrosodimethylamine (NDMA) in various matrices such as water, pharmaceuticals, and food products. Its primary application is in mass spectrometry and gas chromatography methods, where it helps correct for matrix effects and instrument variability, ensuring high precision and reliability in detecting trace levels of this potent carcinogen. Due to its deuterated structure, it behaves similarly to the non-labeled compound during extraction and analysis but can be easily distinguished by the detector, enabling clear identification and measurement.