Used in pharmaceutical research as a potent and selective inhibitor of cyclin-dependent kinases (CDKs), particularly CDK8 and CDK19. It modulates transcriptional regulation by targeting the mediator complex, making it a valuable tool compound in studies related to cancer, inflammation, and gene expression. Shows promising antiproliferative effects in certain leukemia and colorectal cancer cell lines. Also employed in biochemical assays to probe CDK8/CDK19-dependent signaling pathways.