Used primarily in chemotherapy for treating certain types of cancer, including acute myeloid leukemia, acute lymphoblastic leukemia, and advanced prostate cancer. It functions by interfering with DNA replication and RNA synthesis through intercalation and inhibition of topoisomerase II, leading to cancer cell death. Also used in managing multiple sclerosis, particularly secondary progressive forms, to reduce neurologic disability and slow disease progression. Its immunosuppressive properties help control autoimmune activity in the central nervous system. Administered intravenously under medical supervision due to potential cardiotoxicity and other systemic side effects.