Used primarily in the management of hypertension, especially in pregnant women due to its favorable safety profile. It helps lower blood pressure by acting as a centrally acting alpha-2 adrenergic agonist, reducing sympathetic outflow from the central nervous system. Commonly prescribed when other antihypertensives are not suitable during pregnancy, it is effective in controlling gestational hypertension and preventing complications such as preeclampsia. Also used in pediatric hypertension in select cases. Its metabolite, alpha-methylnorepinephrine, activates central receptors leading to decreased peripheral resistance and heart rate. Despite the availability of newer agents, it remains a valuable option in specific patient populations where safety and tolerability are critical.