2-(3-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)piperidin-1-yl)butyl)phenyl)-2-methylpropanoic acid
98%
Reagent
Code: #197341
CAS Number
479035-75-1
blur_circular Chemical Specifications
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Molecular Information
Weight
501.66 g/mol
Formula
C₃₂H₃₉NO₄
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Registry Numbers
MDL Number
MFCD21363595
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Storage & Handling
Storage
2-8°C, sealed, dry
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of second-generation antihistamines. Its structure provides high affinity for peripheral H1 histamine receptors while minimizing penetration of the blood-brain barrier, reducing central nervous system side effects such as sedation. This makes it valuable in developing non-drowsy drugs for allergies, rhinitis, and urticaria. The compound’s functional groups enable selective modifications to optimize pharmacokinetics, receptor specificity, and duration of action. Also utilized in exploring long-acting therapeutic agents due to its favorable metabolic stability and binding profile.
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