Widely used in medicine to enhance the absorption and dispersion of injected drugs, particularly local anesthetics, by breaking down hyaluronic acid in connective tissues. This increases tissue permeability, allowing for faster and more effective delivery of medications. Commonly applied in subcutaneous fluid administration (hypodermoclysis), improving spread and reducing volume buildup. Also utilized in ophthalmic surgery to facilitate anesthesia and improve surgical precision. In fertility treatments, it aids in sperm aspiration procedures. Additionally, employed in diagnostic imaging to enhance the spread of contrast agents. In cosmetic procedures, it is used to dissolve hyaluronic acid-based fillers in cases of complications or for reversal. Its role in reducing tissue barrier resistance makes it valuable across various therapeutic and clinical settings.