Guanethidine Monosulfate
10mM in Water
Reagent
Code: #190110
CAS Number
645-43-2
blur_circular Chemical Specifications
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Molecular Information
Weight
296.39 g/mol
Formula
C₁₀H₂₄N₄O₄S
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in research settings to study the sympathetic nervous system, this compound acts as a sympatholytic agent by depleting norepinephrine from peripheral nerve terminals. It is utilized in experimental models to induce chemical sympathectomy, allowing scientists to investigate the role of sympathetic nerves in various physiological processes such as blood pressure regulation, inflammation, and pain modulation. Due to its ability to selectively damage postganglionic sympathetic neurons, it is also employed in studies related to autonomic dysfunction and neurodegeneration. Its application is largely restricted to laboratory and preclinical research, as it is not commonly used in clinical practice today.
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