6-Fluoro-1,4-dihydro-1-methyl-4-oxo-7-(1-piperazinyl)-3-quinolinecarboxylic acid
Analytical Control
Reagent
Code: #186624
CAS Number
70459-07-3
blur_circular Chemical Specifications
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Molecular Information
Weight
305.3 g/mol
Formula
C₁₅H₁₆FN₃O₃
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Registry Numbers
MDL Number
MFCD04973586
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Storage & Handling
Storage
2-8°C, Sealed
description Product Description
Widely used as an intermediate in the synthesis of fluoroquinolone antibiotics, this compound plays a key role in developing antimicrobial agents effective against a broad spectrum of bacteria. Its structure supports the inhibition of bacterial DNA gyrase and topoisomerase IV, enzymes critical for bacterial DNA replication and repair. As such, it contributes to the production of pharmaceuticals used to treat respiratory, urinary tract, skin, and soft tissue infections. Due to its fluorine and piperazine moieties, it enhances cell penetration and spectrum of activity, especially against Gram-negative and some Gram-positive pathogens. Its derivatives are found in clinically important antibiotics, making it valuable in medicinal chemistry and drug development.
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