Econazole
98%
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Econazole is primarily used as an antifungal agent in the treatment of various fungal infections of the skin, such as athlete’s foot, jock itch, ringworm, and cutaneous candidiasis. It works by inhibiting the synthesis of ergosterol, a vital component of fungal cell membranes, leading to cell membrane disruption and fungal cell death.
It is commonly formulated in topical preparations like creams, sprays, and powders for direct application to affected areas. Due to its broad-spectrum activity against dermatophytes, yeasts, and molds, it is effective in both acute and chronic superficial fungal infections. Econazole also exhibits some antibacterial activity against certain Gram-positive bacteria, which can be beneficial in cases of secondary bacterial infection or mixed microbial involvement.
In addition to dermatological use, econazole has been explored for its potential in veterinary medicine and in the management of oral or mucosal candidiasis in immunocompromised patients. Its lipophilic nature allows for good skin penetration and prolonged local activity, making it a reliable option in outpatient antifungal therapy.
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