Enalaprilat Dihydrate
10mM in DMSO
Reagent
Code: #181326
CAS Number
84680-54-6
blur_circular Chemical Specifications
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Molecular Information
Weight
348.42 g/mol
Formula
C₁₈H₂₄N₂O₅·₂H₂O
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Registry Numbers
MDL Number
MFCD00941393
thermostat
Physical Properties
Melting Point
151-159 °C
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in the treatment of hypertension (high blood pressure) and heart failure. It works by inhibiting the angiotensin-converting enzyme (ACE), which reduces the production of angiotensin II—a substance that narrows blood vessels and increases blood pressure. By blocking this enzyme, it helps blood vessels relax and widen, improving blood flow and reducing the workload on the heart.
Commonly administered in hospital or clinical settings, especially when oral medication is not feasible, as it is available in injectable form. It provides a rapid onset of action, making it suitable for managing acute hypertensive episodes or stabilizing patients before transitioning to oral ACE inhibitors.
Also used in patients following myocardial infarction (heart attack) to improve survival and slow the progression of heart damage by reducing cardiac strain. Its ability to lower systemic vascular resistance makes it beneficial in managing chronic kidney disease associated with diabetes and hypertension, helping to delay the progression of renal impairment.
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