(E)-2-(5-Fluoro-2-methyl-1-(4-(methylsulfinyl)benzylidene)-1H-inden-3-yl)acetic acid
Analytical Control
Reagent
Code: #180796
CAS Number
53933-60-1
blur_circular Chemical Specifications
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Molecular Information
Weight
356.41 g/mol
Formula
C₂₀H₁₇FO₃S
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Registry Numbers
MDL Number
MFCD00057817
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Storage & Handling
Storage
Room temperature, sealed
description Product Description
Used in pharmaceutical research as a key intermediate in the synthesis of selective peroxisome proliferator-activated receptor gamma (PPARγ) modulators. These compounds are investigated for their potential in treating metabolic disorders such as type 2 diabetes due to their ability to regulate glucose and lipid metabolism. The compound's structure allows for high receptor binding affinity and selectivity, making it valuable in developing insulin sensitizers with reduced side effects compared to traditional thiazolidinediones. It is also employed in structure-activity relationship (SAR) studies to optimize drug candidates targeting nuclear receptors involved in metabolic regulation.
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