Used primarily in the treatment of filarial infections, particularly lymphatic filariasis caused by parasitic worms like Wuchereria bancrofti. It works by altering the surface membranes of microfilariae, making them susceptible to the host's immune system. Commonly administered in mass drug administration programs to control the spread of filariasis in endemic regions. Also effective against tropical pulmonary eosinophilia and loiasis. Its ability to clear microfilariae from blood and tissues makes it a key drug in both individual therapy and public health initiatives aimed at eliminating filarial diseases.