Brij is widely used as a non-ionic surfactant in laboratory and industrial applications. It helps in solubilizing membrane proteins by disrupting lipid-lipid and lipid-protein interactions in cell membranes. Commonly used in cell lysis buffers and protein extraction protocols, Brij maintains protein stability while enhancing solubility. It is effective in immunoprecipitation and enzyme assays where mild detergents are required to preserve activity. In cosmetic and pharmaceutical formulations, Brij acts as an emulsifier and solubilizing agent, improving the stability and texture of creams and lotions. Its low toxicity and good biocompatibility make it suitable for use in topical and some parenteral preparations. Brij is also employed in textile processing and agrochemical formulations for its wetting and dispersing properties.