Used primarily to treat bacterial infections, especially those caused by susceptible strains of streptococci and syphilis-causing spirochetes. It is commonly administered as a long-acting intramuscular injection for the treatment of streptococcal pharyngitis, preventing rheumatic fever recurrence. Also effective in managing early and late latent syphilis due to its slow release and prolonged antibiotic activity. Its extended duration allows for less frequent dosing, making it suitable for outpatient and preventive therapy in high-risk populations.