Bleomycin sulfate
10mM in DMSO
Reagent
Code: #142503
CAS Number
9041-93-4
science Other reagents with same CAS 9041-93-4
blur_circular Chemical Specifications
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Molecular Information
Weight
1512.62 g/mol
Formula
C₅₅H₈₅N₁₇O₂₅S₄
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Registry Numbers
EC Number
232-925-2
MDL Number
MFCD00070310
thermostat
Physical Properties
Melting Point
200-204 °C(dec.)
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily as an anticancer agent, particularly in the treatment of Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, and testicular cancer. It is also effective against squamous cell carcinomas, including those of the head, neck, and cervix. Often included in combination chemotherapy regimens due to its unique mechanism of action involving DNA strand breakage. Commonly used in the BEACOPP and ABVD protocols for lymphoma. Also applied in the management of pleural effusions by sclerosing the pleural space to prevent fluid reaccumulation. Its use is limited by pulmonary toxicity, which requires careful monitoring of lung function during treatment.
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