1,4-Bis(4-amino-6,7-dimethoxy-2-quinazolinyl)piperazine, dihydrochloride

Reagent Code: #141519
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CAS Number 1486464-41-8

science Other reagents with same CAS 1486464-41-8

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Weight 565.45 g/mol
Formula C₂₄H₂₈N₈O₄.₂HCl
badge Registry Numbers
MDL Number MFCD04149024
inventory_2 Storage & Handling
Storage -20°C

description Product Description

Used as a key intermediate in the synthesis of vardenafil, a potent inhibitor of phosphodiesterase type 5 (PDE5), this compound plays a critical role in the development of medications for erectile dysfunction and pulmonary arterial hypertension. Its structure enables selective binding and inhibition of PDE5, enhancing smooth muscle relaxation through increased cyclic guanosine monophosphate (cGMP) levels. Due to its high specificity and efficacy, it is preferred in pharmaceutical manufacturing for producing high-purity active pharmaceutical ingredients (APIs). The dihydrochloride salt form improves solubility and stability, facilitating formulation into oral dosage forms.

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Size Availability Unit Price Quantity
inventory 25mg
10-20 days ฿167,600.00
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1,4-Bis(4-amino-6,7-dimethoxy-2-quinazolinyl)piperazine, dihydrochloride
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Used as a key intermediate in the synthesis of vardenafil, a potent inhibitor of phosphodiesterase type 5 (PDE5), this compound plays a critical role in the development of medications for erectile dysfunction and pulmonary arterial hypertension. Its structure enables selective binding and inhibition of PDE5, enhancing smooth muscle relaxation through increased cyclic guanosine monophosphate (cGMP) levels. Due to its high specificity and efficacy, it is preferred in pharmaceutical manufacturing for produc

Used as a key intermediate in the synthesis of vardenafil, a potent inhibitor of phosphodiesterase type 5 (PDE5), this compound plays a critical role in the development of medications for erectile dysfunction and pulmonary arterial hypertension. Its structure enables selective binding and inhibition of PDE5, enhancing smooth muscle relaxation through increased cyclic guanosine monophosphate (cGMP) levels. Due to its high specificity and efficacy, it is preferred in pharmaceutical manufacturing for producing high-purity active pharmaceutical ingredients (APIs). The dihydrochloride salt form improves solubility and stability, facilitating formulation into oral dosage forms.

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