Actein is used in herbal medicine and dietary supplements for its potential adaptogenic and immune-modulating properties. It is commonly found in extracts of black cohosh (Cimicifuga racemosa), which is traditionally used to manage symptoms of menopause, such as hot flashes and sleep disturbances. Research suggests actein may influence serotonin and dopamine pathways, contributing to mood regulation. It has also shown anti-inflammatory and neuroprotective effects in preclinical studies, making it a subject of interest in natural product development for women’s health and cognitive support. However, its mechanisms are not fully understood, and clinical evidence remains limited.