Used in cosmetics for its skin-lightening properties, aloin is incorporated into creams and lotions aiming to reduce hyperpigmentation and dark spots. It has also been utilized in some over-the-counter laxatives due to its stimulant effect on bowel movements. In traditional medicine, it is applied topically for wound healing and to soothe skin irritations. However, its use in oral products has declined due to safety concerns related to potential carcinogenicity. Aloin also finds application in research settings for studying cell apoptosis and inflammation pathways.