5-Aza-2'-deoxycytidine
10mM in DMSO
Reagent
Code: #134436
CAS Number
2353-33-5
science Other reagents with same CAS 2353-33-5
blur_circular Chemical Specifications
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Molecular Information
Weight
228.21 g/mol
Formula
C₈H₁₂N₄O₄
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Registry Numbers
EC Number
219-089-4
MDL Number
MFCD00043011
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily in epigenetic research and cancer therapy, this compound acts as a DNA methyltransferase inhibitor, leading to demethylation of DNA and reactivation of silenced genes, particularly tumor suppressor genes. It is employed in the treatment of myelodysplastic syndromes and acute myeloid leukemia. Its ability to reverse abnormal gene methylation patterns makes it valuable in studying gene regulation, cellular differentiation, and potential therapies for other cancers and genetic disorders.
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