Sinomenine is primarily used in traditional Chinese medicine for its anti-inflammatory and immunosuppressive properties. It is commonly applied in the treatment of rheumatoid arthritis, where it helps reduce joint swelling and pain by modulating immune responses. Additionally, it has shown potential in managing autoimmune diseases by inhibiting the overactivity of the immune system. Recent research also explores its role in alleviating neuropathic pain and its potential anticancer effects, particularly in inhibiting tumor growth and metastasis. Its ability to suppress inflammation makes it a candidate for treating other inflammatory conditions, such as asthma and allergic reactions.