Nebivolol is primarily used in the treatment of high blood pressure (hypertension). It works by relaxing blood vessels and slowing the heart rate, which helps to lower blood pressure and improve blood flow. This medication is often prescribed to reduce the risk of cardiovascular events such as heart attacks and strokes in patients with hypertension. Additionally, Nebivolol is sometimes used in the management of chronic heart failure, where it helps to improve symptoms and increase the patient's ability to exercise. It is particularly beneficial for patients who may not tolerate other beta-blockers well, as it has a more favorable side effect profile, including fewer effects on lipid and glucose metabolism.