SKF-525A Hydrochloride
10mM in DMSO
Reagent
Code: #234084
CAS Number
62-68-0
blur_circular Chemical Specifications
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Molecular Information
Weight
389.96 g/mol
Formula
C₂₃H₃₁NO₂ · HCl
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Registry Numbers
MDL Number
MFCD00055151
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Storage & Handling
Storage
-20°C
description Product Description
Used primarily as a research tool in pharmacology and toxicology studies, this compound acts as a potent inhibitor of cytochrome P450 enzymes, particularly CYP2B and CYP3A subfamilies. It is widely employed to investigate drug metabolism pathways by blocking the biotransformation of test compounds in vitro and in vivo. Researchers use it to assess the role of metabolic activation in drug toxicity and carcinogenicity, as well as to prolong the half-life of certain drugs in experimental models. It has also been applied in studies examining the impact of impaired liver metabolism on pharmacokinetics and drug-drug interactions. Due to its inhibitory effects, it helps distinguish between parent drug effects and those of active metabolites.
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